The smoke produced by the combustion of tobacco in a combustible cigarette (CC) is a complex and dynamic chemical mixture which contains more than 8,000 identified chemical compounds1.
Tobacco smoke from CC consists of an aerosol containing liquid droplets (‘particulate phase’) suspended in a carrier gas and surrounded by its own gas-vapor phase.
Assessment of physical properties of the smoke or aerosol, such as particle size distribution, is important to assess breathability and estimate lung deposition of the chemicals contained in the dropplets.
Particle size and deposition of mainstream cigarette smoke particles depend on the smoking parameters2, and it is therefore important that those characteristics are investigated under different smoking regimen3.
Moreover, the chemical composition of the aeorosol, especially its content in harmful and potentially harmful constituents (HPHCs)3,4, will help determining levels of exposure.